PanFoMa: A Lightweight Foundation Model and Benchmark for Pan-Cancer

arXiv — cs.CVThursday, December 4, 2025 at 5:00:00 AM
  • PanFoMa has been introduced as a lightweight hybrid neural network model designed to enhance pan-cancer research by addressing challenges in learning efficient single-cell representations and establishing a comprehensive evaluation benchmark. This model integrates the capabilities of Transformers and state-space models, enabling effective transcriptome modeling and capturing complex gene interactions.
  • The development of PanFoMa is significant as it aims to improve the understanding of tumor heterogeneity, which is crucial for advancing cancer research and treatment strategies. By providing a more efficient and expressive tool for researchers, it could lead to better insights into cancer biology and therapeutic approaches.
  • This advancement reflects a broader trend in artificial intelligence where hybrid models are increasingly utilized to tackle complex biological problems. The integration of various modeling techniques, such as Mamba and Transformers, highlights the ongoing evolution in computational methods aimed at enhancing accuracy and efficiency in medical research, particularly in the fields of genomics and drug discovery.
— via World Pulse Now AI Editorial System

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