arXiv:2511.08866v1 Announce Type: new 
Abstract: Hypothesis generation in biomedical research has traditionally centered on uncovering hidden relationships within vast scientific literature, often using methods like Literature-Based Discovery (LBD). Despite progress, current approaches typically depend on single data types or predefined extraction patterns, which restricts the discovery of novel and complex connections. Recent advances in Large Language Model (LLM) agents show significant potential, with capabilities in information retrieval, reasoning, and generation. However, their application to biomedical hypothesis generation has been limited by the absence of standardized datasets and execution environments. To address this, we introduce BioVerge, a comprehensive benchmark, and BioVerge Agent, an LLM-based agent framework, to create a standardized environment for exploring biomedical hypothesis generation at the frontier of existing scientific knowledge. Our dataset includes structured and textual data derived from historical biomedical hypotheses and PubMed literature, organized to support exploration by LLM agents. BioVerge Agent utilizes a ReAct-based approach with distinct Generation and Evaluation modules that iteratively produce and self-assess hypothesis proposals. Through extensive experimentation, we uncover key insights: 1) different architectures of BioVerge Agent influence exploration diversity and reasoning strategies; 2) structured and textual information sources each provide unique, critical contexts that enhance hypothesis generation; and 3) self-evaluation significantly improves the novelty and relevance of proposed hypotheses.

تم تقديم BioVerge، معيار جديد لتوليد الفرضيات الطبية الحيوية، لتحسين قدرات وكلاء نماذج اللغة الكبيرة (LLM). تعتمد الأساليب التقليدية غالبًا على أنواع بيانات محدودة، مما يعيق اكتشاف العلاقات المعقدة. يهدف BioVerge إلى توحيد البيئة لتوليد الفرضيات، باستخدام بيانات هيكلية ونصية مستمدة من فرضيات طبية حيوية تاريخية وأدب PubMed. هذه الخطوة مهمة لأنها قد تؤدي إلى نتائج بحثية أكثر ابتكارًا في المجال الطبي الحيوي.

BioVerge, un nuevo estándar para la generación de hipótesis biomédicas, fue presentado para mejorar las capacidades de los agentes de Modelos de Lenguaje Grande (LLM). Los métodos tradicionales a menudo dependen de tipos de datos limitados, lo que dificulta el descubrimiento de relaciones complejas. BioVerge busca estandarizar el entorno para la generación de hipótesis, utilizando datos estructurados y textuales derivados de hipótesis biomédicas históricas y literatura de PubMed. Este avance es significativo, ya que podría conducir a resultados de investigación más innovadores en el campo biomédico.

BioVerge, une nouvelle référence pour la génération d'hypothèses biomédicales, a été introduite pour améliorer les capacités des agents de modèles de langage de grande taille (LLM). Les méthodes traditionnelles reposent souvent sur des types de données limités, entravant la découverte de relations complexes. BioVerge vise à standardiser l'environnement pour la génération d'hypothèses, en utilisant des données structurées et textuelles provenant d'hypothèses biomédicales historiques et de la littérature PubMed. Cette avancée est significative car elle pourrait conduire à des résultats de recherche plus innovants dans le domaine biomédical.

BioVerge, a new benchmark for biomedical hypothesis generation, was introduced to enhance the capabilities of Large Language Model (LLM) agents. Traditional methods often rely on limited data types, hindering the discovery of complex relationships. BioVerge aims to standardize the environment for hypothesis generation, utilizing structured and textual data from historical biomedical hypotheses and PubMed literature. This advancement is significant as it could lead to more innovative research outcomes in the biomedical field.

BioVerge: A Comprehensive Benchmark and Study of Self-Evaluating Agents for Biomedical Hypothesis Generation

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<h1>
 
 
 AI Amnesia: Erasing Knowledge Without a Trace
</h1>

Imagine your AI model accidentally learned something it shouldn't have – sensitive customer data, for example. Current methods for deleting this information often require retraining the entire model, an expensive and time-consuming process. What if we could surgically remove that knowledge without starting from scratch?

The key lies in a novel approach: creating artificial "forgetting cues." We're teaching the model to unlearn specific data patterns by exposing it to carefully crafted synthetic examples. These examples are designed to strongly contradict the information we want the model to forget, effectively overwriting the problematic associations in its memory. This works even if you don’t have access to the original data you need to erase.

Think of it like this: you're trying to forget a bad song stuck in your head. Instead of trying to actively suppress it (which rarely works), you blast an even more catchy song. The new song overwrites the old one, effectively erasing it from your mental playlist.

Benefits of Selective Forgetting:

<ul>
<li> Enhanced Data Privacy: Remove sensitive data without compromising the overall model's performance.</li>
<li> Reduced Retraining Costs: Avoid full model retraining, saving significant time and resources.</li>
<li> Improved Model Security: Eliminate vulnerabilities introduced by unintentionally learned patterns.</li>
<li> Adaptable Learning: Enables continuous refinement of AI models based on evolving data landscapes.</li>
<li> Compliance Ready: Supports compliance with data privacy regulations like GDPR.</li>
<li> Scalable Solutions: Works efficiently even with limited access to training data.</li>
</ul>

Practical Tip: One challenge is ensuring the synthetic data accurately targets the information you want to remove without negatively impacting the model's ability to generalize. Rigorous testing and validation with holdout datasets are crucial.

The promise of AI that can truly 'forget' opens exciting possibilities for responsible AI development. By enabling precise data deletion, we pave the way for more secure, compliant, and adaptable machine learning systems. Imagine AI models that can adapt to changing ethical guidelines or quickly unlearn incorrect information, all without massive retraining efforts. This is a crucial step towards trustworthy and responsible AI that respects data privacy and aligns with societal values. Future exploration could include extending this to different data modalities and model architectures.

Related Keywords: machine unlearning, data privacy, few-shot learning, zero-shot learning, synthetic data, model editing, catastrophic forgetting, incremental learning, continual learning, deep learning, neural networks, data security, algorithmic fairness, responsible ai, ethical ai, federated unlearning, privacy-preserving ai, model retraining, AI governance, data deletion, GDPR compliance

يتناول المقال نهجًا جديدًا لمعالجة مشكلة نسيان الذكاء الاصطناعي، حيث قد تحتفظ نماذج الذكاء الاصطناعي عن غير قصد بمعلومات حساسة. تتطلب الطرق التقليدية لحذف هذه البيانات غالبًا إعادة تدريب كاملة للنموذج، وهو ما يعد مكلفًا ويستغرق وقتًا. تتضمن التقنية الجديدة إنشاء 'إشارات نسيان' اصطناعية تساعد النموذج على نسيان أنماط بيانات معينة من خلال تعريضه لأمثلة صناعية تتناقض مع المعلومات غير المرغوب فيها، مما يسمح بإزالة المعرفة المستهدفة دون الحاجة للوصول إلى البيانات الأصلية.

El artículo aborda un nuevo enfoque para tratar el problema de la amnesia de la IA, donde los modelos de IA pueden retener inadvertidamente información sensible. Los métodos tradicionales para eliminar estos datos a menudo requieren un reentrenamiento completo del modelo, lo que es costoso y lleva tiempo. La nueva técnica implica crear 'señales de olvido' artificiales que ayudan al modelo a desaprender patrones de datos específicos al exponerlo a ejemplos sintéticos que contradicen la información no deseada, permitiendo así la eliminación selectiva de conocimientos sin necesidad de acceder a l…

L'article traite d'une nouvelle approche pour résoudre le problème de l'amnésie de l'IA, où les modèles d'IA peuvent involontairement conserver des informations sensibles. Les méthodes traditionnelles pour supprimer ces données nécessitent souvent un réentraînement complet du modèle, ce qui est coûteux et long. La nouvelle technique consiste à créer des 'cues d'oubli' artificiels qui aident le modèle à désapprendre des schémas de données spécifiques en lui présentant des exemples synthétiques qui contredisent les informations indésirables, permettant ainsi une suppression ciblée des connaissan…

The article discusses a novel approach to address the issue of AI amnesia, where AI models may inadvertently retain sensitive information. Traditional methods for deleting such data often require complete retraining of the model, which is costly and time-consuming. The new technique involves creating artificial 'forgetting cues' that help the model unlearn specific data patterns by presenting it with synthetic examples that contradict the unwanted information, allowing for targeted knowledge removal without needing access to the original data.

AI Amnesia: Erasing Knowledge Without a Trace

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Turning materials like wood chips, crop residues and municipal solid waste into fuels and chemicals is important for our country's energy independence.

طور الباحثون نماذج حاسوبية متقدمة تهدف إلى تحسين التنبؤات لعمليات طحن الكتلة الحيوية. تركز هذه الابتكارات على تحويل مواد مثل رقائق الخشب، بقايا المحاصيل، والنفايات الصلبة البلدية إلى وقود ومواد كيميائية قيمة، وهو أمر مهم لتعزيز استقلالية الطاقة في البلاد. من المتوقع أن تعمل النماذج على تحسين كفاءة معالجة الكتلة الحيوية، مما يساهم في حلول الطاقة المستدامة.

Investigadores han desarrollado modelos informáticos avanzados destinados a mejorar las predicciones para los procesos de molienda de biomasa. Esta innovación se centra en convertir materiales como astillas de madera, residuos de cultivos y residuos sólidos municipales en combustibles y productos químicos valiosos, lo que es crucial para mejorar la independencia energética del país. Se espera que los modelos optimicen la eficiencia del procesamiento de biomasa, contribuyendo así a soluciones energéticas sostenibles.

Des chercheurs ont développé des modèles informatiques avancés visant à améliorer les prévisions pour les processus de broyage de la biomasse. Cette innovation se concentre sur la conversion de matériaux tels que les copeaux de bois, les résidus de culture et les déchets solides municipaux en combustibles et produits chimiques précieux, ce qui est crucial pour renforcer l'indépendance énergétique du pays. Les modèles devraient optimiser l'efficacité du traitement de la biomasse, contribuant ainsi à des solutions énergétiques durables.

Researchers have developed advanced computer models aimed at improving predictions for biomass milling processes. This innovation focuses on converting materials such as wood chips, crop residues, and municipal solid waste into valuable fuels and chemicals, which is crucial for enhancing energy independence in the country. The models are expected to optimize the efficiency of biomass processing, thereby contributing to sustainable energy solutions.

Researchers develop computer models for better biomass milling predictions

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arXiv:2510.24021v2 Announce Type: replace 
Abstract: Knowledge distillation (KD) is a standard route to compress Large Language Models (LLMs) into compact students, yet most pipelines uniformly apply token-wise loss regardless of teacher confidence. This indiscriminate supervision amplifies noisy, high-entropy signals and is especially harmful under large teacher-student capacity gaps. We introduce SelecTKD, a plug-and-play Selective Token-Weighted distillation framework that shifts the focus from "how to measure divergence" to "where to apply learning". At each step, the student proposes tokens that are verified by the teacher through a robust propose-and-verify procedure with two variants: greedy Top-k and non-greedy Spec-k. Accepted tokens receive full loss, while rejected tokens are masked or down-weighted. This objective-agnostic design works with on- and off-policy data, induces an implicit curriculum quantified by Token Acceptance Rate (TAR), and stabilizes optimization. Across instruction following, mathematical reasoning, code generation, and a VLM setting, SelecTKD consistently improves strong baselines and achieves state-of-the-art results for small models without architectural changes or extra reference models.

SelecTKD: Selective Token-Weighted Knowledge Distillation for LLMs

arXiv:2511.13368v1 Announce Type: new 
Abstract: Large language models (LLMs) perform strongly across tasks and languages, yet how improvements in one task or language affect other tasks and languages and their combinations remains poorly understood. We conduct a controlled PEFT/LoRA study across multiple open-weight LLM families and sizes, treating task and language as transfer axes while conditioning on model family and size; we fine-tune each model on a single task-language source and measure transfer as the percentage-point change versus its baseline score when evaluated on all other task-language target pairs. We decompose transfer into (i) Matched-Task (Cross-Language), (ii) Matched-Language (Cross-Task), and (iii) Cross-Task (Cross-Language) regimes. We uncover two consistent general patterns. First, a pronounced on-task vs. off-task asymmetry: Matched-Task (Cross-Language) transfer is reliably positive, whereas off-task transfer often incurs collateral degradation. Second, a stable donor-recipient structure across languages and tasks (hub donors vs. brittle recipients). We outline implications for risk-aware fine-tuning and model specialisation.

Donors and Recipients: On Asymmetric Transfer Across Tasks and Languages with Parameter-Efficient Fine-Tuning

arXiv:2511.11878v1 Announce Type: new 
Abstract: While large language models (LLMs) show transformative potential in healthcare, their development remains focused on high-resource languages, creating a critical barrier for others as simple translation fails to capture unique clinical and cultural nuances, such as endemic diseases. To address this, we introduce MedPT, the first large-scale, real-world corpus for Brazilian Portuguese, comprising 384,095 authentic question-answer pairs from patient-doctor interactions. The dataset underwent a meticulous multi-stage curation protocol, using a hybrid quantitative-qualitative analysis to filter noise and contextually enrich thousands of ambiguous queries. We further augmented the corpus via LLM-driven annotation, classifying questions into seven semantic types to capture user intent. Our analysis reveals its thematic breadth (3,200 topics) and unique linguistic properties, like the natural asymmetry in patient-doctor communication. To validate its utility, we benchmark a medical specialty routing task: fine-tuning a 1.7B parameter model achieves an outstanding 94\% F1-score on a 20-class setup. Furthermore, our qualitative error analysis shows misclassifications are not random but reflect genuine clinical ambiguities (e.g., between comorbid conditions), proving the dataset's deep semantic richness. We publicly release MedPT to foster the development of more equitable, accurate, and culturally-aware medical technologies for the Portuguese-speaking world.

BioVerge: A Comprehensive Benchmark and Study of Self-Evaluating Agents for Biomedical Hypothesis Generation

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