Physics-Informed Neural Operators for Cardiac Electrophysiology

arXiv — cs.LGWednesday, November 12, 2025 at 5:00:00 AM
The recent publication on Physics-Informed Neural Operators (PINO) for cardiac electrophysiology marks a significant advancement in computational modeling. Traditional numerical solvers are often computationally expensive and sensitive to discretization, while existing Physics-Informed Neural Networks (PINNs) struggle with long-term predictive stability and mesh resolution. The proposed PINO approach overcomes these challenges by learning mappings between function spaces, allowing for generalization across multiple mesh resolutions and initial conditions. This capability enables accurate reproduction of cardiac dynamics over extended time horizons, even in scenarios not encountered during training. The results demonstrate that PINO models not only maintain high predictive quality during long roll-outs but also achieve a significant reduction in simulation time compared to traditional methods. This innovation is crucial for enhancing the efficiency and accuracy of cardiac electrophysiol…
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