The Alignment Paradox of Medical Large Language Models in Infertility Care: Decoupling Algorithmic Improvement from Clinical Decision-making Quality

arXiv — cs.LGTuesday, November 25, 2025 at 5:00:00 AM
  • A recent study evaluated the alignment of large language models (LLMs) in infertility care, assessing four strategies: Supervised Fine-Tuning (SFT), Direct Preference Optimization (DPO), Group Relative Policy Optimization (GRPO), and In-Context Learning (ICL). The findings revealed that GRPO achieved the highest algorithmic accuracy, while clinicians preferred SFT for its clearer reasoning and therapeutic feasibility.
  • This development is significant as it highlights the ongoing challenge of integrating advanced AI models into clinical decision-making, particularly in sensitive areas like infertility care. The preference for SFT by clinicians underscores the importance of interpretability and practical applicability in medical AI.
  • The findings reflect broader discussions in the AI field regarding the balance between algorithmic performance and human-centered design. Issues such as hallucination mitigation, bias in model outputs, and the need for diverse reasoning capabilities are critical as LLMs are increasingly utilized in healthcare settings.
— via World Pulse Now AI Editorial System

Was this article worth reading? Share it

Recommended apps based on your readingExplore all apps
Continue Readings
Silence the Judge: Reinforcement Learning with Self-Verifier via Latent Geometric Clustering
PositiveArtificial Intelligence
A new framework called Latent-GRPO has been introduced to enhance the reasoning performance of Large Language Models (LLMs) by deriving intrinsic rewards from latent space geometry, addressing the limitations of traditional Group Relative Policy Optimization (GRPO) that relies on external verifiers.
This AI spots dangerous blood cells doctors often miss
PositiveArtificial Intelligence
A new generative AI system has been developed that can analyze blood cells with greater accuracy than human experts, effectively detecting subtle signs of diseases such as leukemia. This AI not only identifies rare abnormalities but also acknowledges its own uncertainty, providing a valuable support tool for clinicians in diagnosing complex conditions.

Ready to build your own newsroom?

Subscribe to unlock a personalised feed, podcasts, newsletters, and notifications tailored to the topics you actually care about