GP-GPT: Large Language Model for Gene-Phenotype Mapping

arXiv — cs.CLTuesday, November 25, 2025 at 5:00:00 AM
  • GP-GPT has been introduced as the first specialized large language model designed for gene-phenotype mapping, addressing the complexities of multi-source genomic data. This model has been fine-tuned on a vast corpus of over 3 million terms from genomics, proteomics, and medical genetics, showcasing its ability to retrieve medical genetics information and perform genomic analysis tasks effectively.
  • The development of GP-GPT is significant as it represents a breakthrough in bioinformatics, potentially enhancing the accuracy and efficiency of genetic research and analysis. By leveraging advanced natural language processing capabilities, GP-GPT aims to facilitate better understanding and representation of genetic-phenotype relationships.
  • This advancement in large language models reflects a broader trend in the application of AI in healthcare and biomedical research, where models like GPT-4 are being evaluated for various tasks, including pathology localization and sentiment analysis. The ongoing exploration of LLMs in diverse fields underscores their transformative potential, while also raising questions about their limitations and the need for specialized adaptations.
— via World Pulse Now AI Editorial System

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