The Effect of Negation on CLIP in Medical Imaging: Limitations of Contrastive Language-Image Pretraining

arXiv — cs.LGMonday, December 22, 2025 at 5:00:00 AM
  • A recent study evaluated the Stanford AIMI CheXagent model's performance in retrieving chest X-ray images using prompts with and without negation, highlighting the limitations of CLIP-based models in medical imaging tasks. The findings indicate that these models often struggle with negated phrases, which can hinder accurate medical diagnoses.
  • This development is significant as it underscores the challenges faced by large vision-language models like CLIP in clinical settings, where precise interpretation of medical language is crucial for effective patient care.
  • The issue of negation in medical imaging reflects broader concerns about the robustness of AI models in understanding complex language constructs, as similar challenges have been noted in other areas of vision-language learning, including paraphrasing and semantic alignment, suggesting a need for ongoing refinement and innovation in AI methodologies.
— via World Pulse Now AI Editorial System

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