The recent advancements in optimizing Earth-Moon transfer and cislunar navigation are exciting for the future of space exploration. By integrating low-energy trajectories with AI techniques and GNSS-R technologies, researchers are addressing the challenges posed by traditional methods that are often limited by launch windows and propellant needs. This innovation not only enhances the efficiency of lunar missions but also supports the growing activities in cislunar space, such as lunar landings and in-space refueling stations, paving the way for more autonomous and sustainable exploration beyond Earth.