Markerless Augmented Reality Registration for Surgical Guidance: A Multi-Anatomy Clinical Accuracy Study

arXiv — cs.CVWednesday, November 5, 2025 at 5:00:00 AM

Markerless Augmented Reality Registration for Surgical Guidance: A Multi-Anatomy Clinical Accuracy Study

A recent clinical accuracy study evaluated a markerless augmented reality system designed for surgical guidance, utilizing the HoloLens 2 device. This innovative system aligns depth data with CT-derived anatomical models, enabling precise registration without the need for physical markers. Tested across multiple anatomies, the approach demonstrated significant improvements in accuracy during real-life surgeries, particularly for complex anatomical structures. The study's findings support the system's potential to enhance surgical outcomes by providing surgeons with more reliable spatial information. As a markerless solution, it offers practical advantages over traditional methods that rely on markers, potentially streamlining surgical workflows. These results highlight the promise of augmented reality technologies in advancing surgical precision and patient care.

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