Positive Semi-definite Latent Factor Grouping-Boosted Cluster-reasoning Instance Disentangled Learning for WSI Representation

arXiv — cs.CVWednesday, November 5, 2025 at 5:00:00 AM

Positive Semi-definite Latent Factor Grouping-Boosted Cluster-reasoning Instance Disentangled Learning for WSI Representation

A new framework has been introduced to enhance the representation of whole-slide pathology images by addressing challenges inherent in multiple instance learning. This approach, known as Positive Semi-definite Latent Factor Grouping-Boosted Cluster-reasoning Instance Disentangled Learning, aims to disentangle instances within the data, thereby improving both interpretability and representation. By focusing on instance disentanglement, the framework offers a more nuanced understanding of the complex structures present in whole-slide images. This development marks a significant advancement in medical imaging, particularly in the analysis of pathology slides. The framework's introduction has been positively received for its potential to improve the accuracy and clarity of image representations. Overall, this innovative method represents a promising step forward in the application of artificial intelligence to medical diagnostics.

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