Novo Nordisk said a pill with the key ingredient in Ozempic and Wegovy didn’t slow Alzheimer’s disease in two late-stage clinical trials

Dow Jones – HealthMonday, November 24, 2025 at 1:38:00 PM
NegativeHealth
Novo Nordisk said a pill with the key ingredient in Ozempic and Wegovy didn’t slow Alzheimer’s disease in two late-stage clinical trials
  • Novo Nordisk announced that a pill containing the key ingredient from its diabetes and weight-loss drugs, Ozempic and Wegovy, did not demonstrate efficacy in slowing the progression of Alzheimer’s disease during two late-stage clinical trials. This outcome raises concerns about the potential of these medications in treating neurodegenerative conditions.
  • This development is significant for Novo Nordisk as it highlights the limitations of their product portfolio, particularly in expanding into the Alzheimer’s treatment market, which is a critical area of unmet medical need. The failure of these trials may impact investor confidence and future research directions.
  • The results also reflect ongoing challenges in the pharmaceutical industry regarding the development of effective treatments for complex conditions like Alzheimer’s. While there is a push for innovative weight-loss drugs that minimize side effects, the intersection of weight management and neurological health remains a complex and underexplored area, suggesting a need for further research and development.
— via World Pulse Now AI Editorial System

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Joel Habener, Whose Research Led to Weight-Loss Drugs, Dies at 88
NeutralHealth
Joel Habener, a prominent researcher whose work led to the discovery of the protein fragment GLP-1, has passed away at the age of 88. His research was instrumental in the development of significant weight-loss medications such as Ozempic and Wegovy, which have become widely used in treating obesity and diabetes.

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