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'Completely new and totally unexpected finding': Iron deficiency in pregnancy can cause 'male' mice to develop female organs

Live ScienceFriday, June 13, 2025 at 5:30:00 PM
'Completely new and totally unexpected finding': Iron deficiency in pregnancy can cause 'male' mice to develop female organs
Scientists have stumbled onto something wild—iron deficiency in pregnant mice can actually alter the sex development of their offspring. Normally, male (XY) mouse embryos grow male organs, but when moms lacked iron, some of these embryos developed female reproductive features instead. It’s a genetic switcheroo no one saw coming. The big question now: Could this happen in humans too?
Editor’s Note: This isn’t just a quirky mouse mystery—it hints at how fragile early development can be. If iron plays such a dramatic role in sex determination, it could reshape how we think about prenatal nutrition and genetic regulation. For now, though, don’t panic—human biology is way more complex, and this is just the starting point for deeper research.
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