Cardinals WR Marvin Harrison Jr. (appendicitis) out vs. 49ers

Marvin Harrison Jr., a key player for the Arizona Cardinals, has been sidelined due to appendicitis, requiring surgery that will prevent him from participating in the game against the San Francisco 49ers. His absence is particularly impactful given his role in the team's offense, which may struggle without his contributions. The Cardinals will need to adjust their game plan to compensate for his loss, which could affect their performance against a competitive 49ers team. This situation highlights the unpredictability of player health in professional sports and its direct influence on team dynamics and game outcomes.