Kyle Shanahan provides disappointing injury updates on a few 49ers on Monday

The Arizona Cardinals are experiencing a tumultuous season, having started strong but ultimately faltering. Speculation is growing around the future of franchise quarterback Kyler Murray, with indications that he may be nearing the end of his tenure with the team. Amidst these challenges, tight end Trey McBride is on track for a significant career season, showcasing his potential despite the team's struggles.

The Arizona Cardinals have ruled out wide receiver Marvin Harrison Jr. and running back Emari Demercado for their upcoming game against the Jacksonville Jaguars. This decision comes as the team continues to face challenges with player injuries.

The San Francisco 49ers have faced numerous challenges this season, including significant injuries. Despite these setbacks, the team has managed to secure a 6-4 record after ten weeks. The return of quarterback Brock Purdy could signal a turning point for the 49ers as they aim for a playoff spot in the NFC.

The San Francisco 49ers defeated the Arizona Cardinals in Week 11, maintaining their hopes for a playoff berth. Former quarterback Steve Young expressed strong confidence in the team's potential to secure a playoff spot, emphasizing the need for continued effort in the upcoming weeks.

Mac Jones has garnered attention during the 2025 season with the San Francisco 49ers, stepping in effectively for the injured Brock Purdy. Speculation has arisen regarding Jones' future, with some suggesting a potential quarterback controversy between him and Purdy. Mike Florio has floated the idea of the Minnesota Vikings as a possible trade destination for Jones following his resurgence with the 49ers.

As the 2025 season nears its conclusion, speculation about Kyler Murray's future with the Arizona Cardinals intensifies. ESPN's Jeremy Fowler reports that many believe Murray has likely played his last game for the team, prompting questions about the franchise's direction and leadership.

Ryan Fitzpatrick is set to make his debut as a radio analyst for Westwood One during the upcoming 'Monday Night Football' game. This marks a significant career transition for Fitzpatrick, who has previously been known for his role as a quarterback in the NFL. His insights are anticipated to enhance the viewing experience for fans tuning in to the game featuring the San Francisco 49ers and the Carolina Panthers.

The Chicago Bears are currently leading the NFC North with a 7-3 record as they enter Week 12 of the NFL season. However, their playoff aspirations are challenged by a tough schedule ahead, which includes two games against the Green Bay Packers and matches against the Philadelphia Eagles, Pittsburgh Steelers, and San Francisco 49ers. The Bears must navigate this challenging stretch to secure their playoff position.