49ers vs. Cardinals: Injury updates, predictions from 49ers Week 3 opponent

Yahoo SportsSaturday, September 20, 2025 at 3:45:22 PM
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The San Francisco 49ers are gearing up for their Week 3 matchup against the Arizona Cardinals, a team that has posed challenges since Kyle Shanahan became head coach in 2017. This game is significant as it could set the tone for the 49ers' season, especially considering their past struggles against the Cardinals. Fans are eager to see how the team addresses injuries and strategizes to secure a win.
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