Rams vs. San Francisco 49ers: How to watch, start time and prediction

On November 8, 2025, the Rams will compete against the San Francisco 49ers in a crucial Week 10 NFL matchup. This game is particularly important as both teams are known for their competitive spirit and have a storied rivalry. The anticipation surrounding the event includes discussions about predictions on who will win, reflecting the high stakes involved. As the NFL season progresses, matchups like this one not only impact playoff standings but also engage fans and analysts alike, making it a focal point of the sports calendar.