Cardinals RB James Conner carted off in loss to 49ers early with ankle injury, set for season-ending surgery

Yahoo Sports – GeneralSunday, September 21, 2025 at 10:15:36 PM
NegativeSports
In a tough blow for the Arizona Cardinals, running back James Conner was carted off the field during their game against the San Francisco 49ers due to a serious ankle injury. The injury occurred in the second half when Conner was tackled, leading to a season-ending surgery. This is a significant setback for the team as Conner has been a key player, and his absence will be felt in the remaining games of the season.
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