NFL Week 12 bold predictions & key matchups: Chiefs are desperate, Bucs-Rams hoss fight, Caleb Williams top-10 QB?

Keon Coleman, a wide receiver for the Buffalo Bills, has faced challenges leading to his benching since his NFL debut. Despite being healthy, he was inactive during Week 11 against the Tampa Bay Buccaneers, raising questions about his role on the team as they approach Week 12.

The college football season is approaching its conclusion, providing NFL Draft prospects with the opportunity to showcase their abilities. As the 2026 NFL Draft approaches, players' strengths and weaknesses will be further highlighted during the Bowl season and the College Football Playoff, influencing their draft positions.

The Kansas City Chiefs are currently at a critical juncture in the Patrick Mahomes era, holding a 5-5 record. This situation raises concerns about their playoff prospects, as missing the postseason could lead to significant offseason challenges. The team's performance has been under scrutiny, particularly following a recent loss to the Denver Broncos, which has ended their long-standing dominance in the AFC West.

New England Patriots quarterback Drake Maye has significantly improved in his second season, placing him in the NFL MVP conversation. The Patriots have won eight consecutive games and are leading the AFC as they prepare for a Week 12 matchup against the Cincinnati Bengals. Under the guidance of new head coach Mike Vrabel, Maye's performance has been a key factor in the team's success.

Shedeur Sanders is set to make his first NFL start for the Cleveland Browns against the Las Vegas Raiders. This opportunity arises due to starting quarterback Dillon Gabriel being sidelined with a concussion. Scouts and executives have differing opinions on Sanders' readiness for this pivotal moment in his career.

Heading into Week 12 of the 2025 NFL season, Houston Texans running back Joe Mixon has been ruled out for the remainder of the season due to a foot injury. This decision comes as the Texans adjust their roster and strategy in light of Mixon's absence, which has been confirmed by multiple reports.

Josh Allen of the Buffalo Bills demonstrated his MVP credentials by scoring six total touchdowns in Week 11, leading his team to a significant victory over the Tampa Bay Buccaneers. This performance has positioned him favorably in the MVP race as he prepares for a challenging matchup against the Houston Texans in Week 12.

The Chicago Bears' offense is thriving under head coach Ben Johnson, with significant contributions from quarterback Caleb Williams. While Williams' development is a focal point, Johnson's offensive strategies are pivotal to the team's success. The Bears are currently enjoying a strong season, showcasing a well-rounded offensive approach.