John Stamos has been a steadfast supporter of Lori Loughlin throughout her challenges, showcasing their deep friendship that has lasted over four decades. Their bond, which began on the set of the beloved '90s sitcom Full House, highlights the importance of loyalty and support in difficult times. Stamos's unwavering defense of Loughlin not only emphasizes their personal connection but also resonates with fans who appreciate the enduring nature of their relationship.

John Stamos has come to the defense of his former co-star Lori Loughlin, criticizing her ex-husband Mossimo Giannulli as a 'narcissist.' This public support highlights the strong bond among the 'Full House' cast, showcasing their loyalty to one another amidst personal controversies. Stamos's remarks not only reflect his friendship with Loughlin but also resonate with fans who appreciate the camaraderie of the beloved sitcom family.