Nick Bosa Ruled Out with Knee Injury, Raising Concerns for 49ers

San Francisco 49ers star defensive player Nick Bosa has been ruled out for the remainder of the game against the Arizona Cardinals due to a knee injury. His reaction of giving a thumbs down while leaving the medical tent indicates the seriousness of the injury. This development is troubling for the 49ers, who are already dealing with multiple injuries this season, as Bosa's absence could significantly affect the team's defensive strategy and overall performance.