Beyond accuracy: quantifying the reliability of Multiple Instance Learning for Whole Slide Image classification

arXiv — cs.CVWednesday, December 10, 2025 at 5:00:00 AM
  • A recent study has introduced three quantitative metrics to assess the reliability of Multiple Instance Learning (MIL) models used for Whole Slide Image (WSI) classification in computational pathology. The research highlights a significant gap in evaluating the reliability of these models, which are crucial for clinical decision-making. The mean pooling instance model (MEAN-POOL-INS) was found to be the most reliable among the tested architectures.
  • The findings underscore the importance of reliability in machine learning applications, particularly in high-stakes environments such as healthcare. As the use of AI in clinical settings grows, ensuring that models produce trustworthy and consistent predictions is essential for patient safety and effective diagnosis.
  • This development reflects a broader trend in the field of computational pathology, where various innovative frameworks and methodologies are being explored to enhance the accuracy and interpretability of WSI analysis. The integration of advanced techniques, such as vision-language models and probabilistic spatial attention, indicates a shift towards more robust and reliable AI systems that can better support medical professionals in their diagnostic processes.
— via World Pulse Now AI Editorial System

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