When normalization hallucinates: unseen risks in AI-powered whole slide image processing
NegativeArtificial Intelligence
- Whole slide image (WSI) normalization is increasingly utilized in computational pathology, driven by deep learning techniques. However, recent findings indicate that these models may produce hallucinated content—artifacts that appear realistic but are not present in the original tissue—compromising diagnostic accuracy and posing significant risks in clinical settings.
- The emergence of hallucinations in AI-powered WSI processing raises concerns about the reliability of deep learning models in pathology. As these models are retrained on real-world clinical data, the frequency of hallucinations suggests a critical need for improved evaluation practices to ensure patient safety and diagnostic integrity.
- The challenges of hallucinations in AI models highlight a broader issue within computational pathology, where advancements in deep learning must be balanced with rigorous validation methods. As the field evolves, the integration of frameworks that enhance interpretability and address data distribution discrepancies will be essential to mitigate risks and improve clinical outcomes.
— via World Pulse Now AI Editorial System
