G2L:From Giga-Scale to Cancer-Specific Large-Scale Pathology Foundation Models via Knowledge Distillation

arXiv — cs.CVMonday, December 22, 2025 at 5:00:00 AM
  • Recent advancements in pathology foundation models have led to the introduction of the G2L framework, which enhances the performance of large-scale models to match that of giga-scale models while using significantly fewer parameters and training data. This approach utilizes knowledge distillation, transferring capabilities from larger models to smaller ones with just 1,000 pathology slides of specific cancer types.
  • The G2L framework addresses the high computational costs associated with giga-scale models, making advanced cancer diagnostics more accessible and efficient. By reducing the resource requirements, it opens avenues for broader application in clinical settings, potentially improving patient outcomes.
  • This development highlights ongoing challenges in the field of medical imaging, particularly regarding the limitations of current foundation models, which often struggle with accuracy and stability. The G2L framework represents a shift towards more practical solutions in cancer detection and analysis, amidst a backdrop of evolving technologies aimed at enhancing diagnostic precision and efficiency in pathology.
— via World Pulse Now AI Editorial System

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