MedSAM3: Delving into Segment Anything with Medical Concepts

arXiv — cs.CVTuesday, November 25, 2025 at 5:00:00 AM
  • MedSAM-3 has been introduced as a text promptable medical segmentation model designed to enhance medical image and video segmentation by allowing precise targeting of anatomical structures through open-vocabulary text descriptions. This model builds on the Segment Anything Model (SAM) 3 architecture, addressing the limitations of existing methods that require extensive manual annotation for clinical applications.
  • This development is significant as it streamlines the segmentation process in medical imaging, potentially reducing the time and effort required for manual annotations. By integrating Multimodal Large Language Models (MLLMs), MedSAM-3 can perform complex reasoning and iterative refinement, enhancing its utility in clinical settings.
  • The introduction of MedSAM-3 reflects a broader trend in artificial intelligence towards improving generalizability and efficiency in medical imaging. This aligns with ongoing efforts to develop label-efficient segmentation techniques and frameworks that address challenges such as limited annotated data and the need for cross-modality generalization, which are critical for advancing medical diagnostics and treatment planning.
— via World Pulse Now AI Editorial System

Was this article worth reading? Share it

Recommended apps based on your readingExplore all apps
Continue Readings
Where Does Vision Meet Language? Understanding and Refining Visual Fusion in MLLMs via Contrastive Attention
PositiveArtificial Intelligence
A recent study has explored the integration of visual and textual information in Multimodal Large Language Models (MLLMs), revealing that visual-text fusion occurs at specific layers within these models rather than uniformly across the network. The research highlights a late-stage
Incentivizing Cardiologist-Like Reasoning in MLLMs for Interpretable Echocardiographic Diagnosis
PositiveArtificial Intelligence
A novel approach has been proposed to enhance echocardiographic diagnosis through the integration of a Cardiac Reasoning Template (CRT) and CardiacMind, aimed at improving the reasoning capabilities of multimodal large language models (MLLMs). This method addresses the challenges faced by existing models in capturing the relationship between quantitative measurements and clinical manifestations in cardiac screening.
ISLA: A U-Net for MRI-based acute ischemic stroke lesion segmentation with deep supervision, attention, domain adaptation, and ensemble learning
PositiveArtificial Intelligence
A new deep learning model named ISLA (Ischemic Stroke Lesion Analyzer) has been introduced for the segmentation of acute ischemic stroke lesions in MRI scans. This model leverages the U-Net architecture and incorporates deep supervision, attention mechanisms, and domain adaptation, trained on over 1500 participants from multiple centers.
Sesame Plant Segmentation Dataset: A YOLO Formatted Annotated Dataset
PositiveArtificial Intelligence
A new dataset, the Sesame Plant Segmentation Dataset, has been introduced, featuring 206 training images, 43 validation images, and 43 test images formatted for YOLO segmentation. This dataset focuses on sesame plants at early growth stages, captured under various environmental conditions in Nigeria, and annotated with the Segment Anything Model version 2.
Exploiting DINOv3-Based Self-Supervised Features for Robust Few-Shot Medical Image Segmentation
PositiveArtificial Intelligence
A novel framework named DINO-AugSeg has been proposed to enhance few-shot medical image segmentation by leveraging DINOv3-based self-supervised features. This approach addresses the challenge of limited annotated training data in clinical settings, utilizing wavelet-based feature-level augmentation and contextual information-guided fusion to improve segmentation accuracy across various imaging modalities such as MRI and CT.
Unified Multi-Site Multi-Sequence Brain MRI Harmonization Enriched by Biomedical Semantic Style
PositiveArtificial Intelligence
A new framework, MMH, has been introduced for unified multi-site multi-sequence brain MRI harmonization, addressing the challenges of non-biological heterogeneity in MRI data caused by site-specific variations. This method aims to standardize image style while preserving anatomical content, enhancing the training of deep learning models.
UR-Bench: A Benchmark for Multi-Hop Reasoning over Ultra-High-Resolution Images
NeutralArtificial Intelligence
The introduction of the Ultra-high-resolution Reasoning Benchmark (UR-Bench) aims to evaluate the reasoning capabilities of multimodal large language models (MLLMs) specifically on ultra-high-resolution images, which have been largely unexplored in existing visual question answering benchmarks. This benchmark features two main categories, Humanistic Scenes and Natural Scenes, with images ranging from hundreds of megapixels to gigapixels, accompanied by structured questions.
Automated Lesion Segmentation of Stroke MRI Using nnU-Net: A Comprehensive External Validation Across Acute and Chronic Lesions
PositiveArtificial Intelligence
A comprehensive external validation of the nnU-Net framework for automated lesion segmentation in stroke MRI has been conducted, demonstrating robust generalization across various datasets and imaging modalities, including DWI, FLAIR, and T1-weighted MRI. This study highlights the importance of accurate lesion delineation for clinical research and personalized interventions in stroke management.

Ready to build your own newsroom?

Subscribe to unlock a personalised feed, podcasts, newsletters, and notifications tailored to the topics you actually care about