Obesity jab drug fails to slow Alzheimer's

BBC NewsMonday, November 24, 2025 at 5:13:38 PM
NegativeHealth
Obesity jab drug fails to slow Alzheimer's
  • Novo Nordisk's weight loss drug Wegovy has failed to demonstrate any efficacy in slowing the progression of Alzheimer's disease, according to recent trials. Initial hopes were pinned on the drug's potential to impact cognitive decline positively, but results have shown no significant benefits for patients with dementia or mild cognitive impairment.
  • This setback is significant for Novo Nordisk as it undermines the company's ambitions to expand the therapeutic applications of Wegovy and its other diabetes drug, Ozempic, which shares similar active ingredients. The failure to show cognitive benefits may affect investor confidence and future research directions.
  • The broader implications of this development highlight ongoing challenges in the pharmaceutical industry regarding the effectiveness of weight loss drugs on neurological conditions. While Wegovy and similar medications are recognized for their weight loss capabilities, concerns about their side effects and overall impact on brain health continue to prompt further research and scrutiny.
— via World Pulse Now AI Editorial System

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Ozempic Drug Fails to Quell Alzheimer’s in Novo Nordisk Trials
NegativeHealth
Novo Nordisk's trials of its diabetes and weight loss drug, Ozempic, have failed to demonstrate any positive effects on cognition or functioning in individuals with mild cognitive impairment or dementia, marking a significant setback for the company's ambitions in treating Alzheimer's disease.
Novo Nordisk said a pill with the key ingredient in Ozempic and Wegovy didn’t slow Alzheimer’s disease in two late-stage clinical trials
NegativeHealth
Novo Nordisk announced that a pill containing the key ingredient from its diabetes and weight-loss drugs, Ozempic and Wegovy, did not demonstrate efficacy in slowing the progression of Alzheimer’s disease during two late-stage clinical trials. This outcome raises concerns about the potential of these medications in treating neurodegenerative conditions.