Moleculin receives Canadian patent allowance for cancer drug Annamycin

Starbucks is making significant cuts by closing 1% of its stores in the US and Canada and laying off 900 employees. This move reflects the company's efforts to save money amid pressures from Wall Street, which has been pushing for deeper reductions given Starbucks' large workforce of 360,000 and its extensive global presence of 41,000 locations. These changes could impact customer access and employee morale, highlighting the challenges the company faces in a competitive market.

Mark Leonard, the founder and president of Constellation Software, has resigned due to health issues, leading to a significant drop in the company's stock price and a downgrade from analysts. This news is concerning as Leonard was seen as an irreplaceable leader, and his departure raises questions about the company's future direction and stability in the tech sector.

Canada's fiscal watchdog has warned that the country's budget deficit is set to widen, exceeding 2% of the economy in the near term. This projection comes amid weak economic growth and new spending measures proposed by Prime Minister Mark Carney aimed at restructuring the economy. The implications of these deficits could affect public services and economic stability, making it a critical issue for Canadians.

Donald Trump's steel tariffs are causing significant backlash not just from affected industries but also from neighboring countries like Mexico, Brazil, and Canada. These nations are responding to the tariffs, which are seen as detrimental to global trade relations. This situation is crucial as it highlights the ripple effects of unilateral trade policies and raises concerns about escalating tensions in international trade.

DeFi Technologies has made a strategic investment in Canada-based Stablecorp to enhance the scalability of its QCAD stablecoin. This move is significant as it highlights the growing interest and potential of stablecoins in the cryptocurrency market, particularly in Canada. By investing in Stablecorp, DeFi Technologies aims to strengthen its position in the digital currency landscape, which could lead to increased adoption and usage of QCAD, benefiting both companies and their users.

Gas prices in Canada are experiencing a significant drop, thanks to seasonal changes and the removal of the consumer carbon price, which is leading to even greater savings for consumers. This is great news for drivers, as it means more money in their pockets during a time when fuel costs can be a burden. With prices heading towards some of the lowest levels of the year, many are hopeful that this trend could continue, making travel and commuting more affordable.

A coalition of ten environmental groups is urging the Bank of England to take stronger action against the climate crisis, marking ten years since Mark Carney's pivotal speech on the issue. Carney, who is now the Prime Minister of Canada, highlighted the urgent need for long-term thinking in financial policies to combat climate change. This renewed call to action emphasizes the importance of addressing climate issues before it's too late, reflecting a growing recognition of the financial sector's role in environmental sustainability.

Canada is taking significant steps to enhance its trade relationship with Indonesia, aiming to diversify its exports beyond the United States. This initiative, announced by a Canadian minister, highlights the importance of expanding trade partnerships in a global economy that is increasingly interconnected. By boosting exports to Indonesia, Canada not only strengthens its economic ties but also opens up new markets for its goods, which is crucial for long-term growth and stability.

A former employee of RBC has been charged with unauthorized access to the banking profile of Canada's Prime Minister, Mark Carney. This incident raises serious concerns about privacy and security within financial institutions, especially regarding sensitive information of public figures. The implications of such breaches can undermine public trust in banking systems and highlight the need for stricter regulations and safeguards.

Canada's population growth rate is nearing zero due to government measures aimed at reducing the temporary migrant population. This is significant as it highlights the impact of immigration policies on demographic trends, potentially affecting the economy and labor market.

Factory sales in Canada are estimated to have dropped by 1.5% in August, indicating a slowdown in manufacturing activity after a brief recovery in the previous months. This decline is concerning as it suggests potential challenges for the Canadian economy, impacting jobs and growth.

The US FDA has declined to approve a higher dose of Biogen's drug aimed at treating genetic disorders, which is a setback for the company and patients hoping for more effective treatment options. This decision highlights the ongoing challenges in the pharmaceutical industry regarding drug approvals and raises questions about the future of Biogen's product pipeline.

Starbucks has announced plans to close several underperforming stores in the US and UK as part of a restructuring effort aimed at saving costs. This move highlights the challenges the coffee giant faces in maintaining profitability amid changing consumer habits and economic pressures. While it may help streamline operations, the closures could impact local communities and employees, raising concerns about job losses and reduced access to their favorite coffee spots.

Ticketmaster U.K. has agreed to implement changes following public outrage over its handling of Oasis ticket sales. This decision is significant as it reflects the company's responsiveness to customer concerns and aims to improve the ticket purchasing experience for fans. By addressing these issues, Ticketmaster hopes to restore trust and ensure that fans have fair access to tickets for their favorite artists.

Palestinian President Mahmoud Abbas has called for an immediate end to the ongoing war in Gaza during a video address to the UN General Assembly. He emphasized the need for the release of hostages on both sides and rejected Hamas's actions against Israel on October 7. This appeal for peace is significant as it highlights the urgent need for dialogue and resolution in a conflict that has caused immense suffering. Meanwhile, Israeli Prime Minister Benjamin Netanyahu is set to address the assembly in person, indicating the international attention this crisis continues to attract.

Smart investors are currently focusing on key opportunities that promise strong returns, according to a market strategist. This insight is crucial as it highlights where to allocate resources effectively in today's dynamic financial landscape, helping individuals and businesses make informed decisions.

After an impressive 103 years in business, a well-known sporting goods retailer is closing its doors for good. This closure marks the end of an era for a company that has been a staple in the community, providing not just products but also a sense of belonging for sports enthusiasts. The loss of such a long-standing retailer highlights the challenges faced by traditional businesses in today's market, making it a significant event for both employees and loyal customers.

The rise of drones is transforming modern warfare, with unmanned aerial systems becoming essential for military operations. As defense spending continues to soar, the demand for these advanced technologies is expected to double, highlighting their growing importance in national security strategies. This shift not only reflects advancements in technology but also indicates a significant change in how conflicts may be approached in the future.