MambaMIL+: Modeling Long-Term Contextual Patterns for Gigapixel Whole Slide Image

arXiv — cs.CVMonday, December 22, 2025 at 5:00:00 AM
  • A new framework, MambaMIL+, has been proposed to enhance the analysis of whole-slide images (WSIs) in computational pathology by effectively integrating spatial context and maintaining long-range dependencies without memory decay. This advancement addresses the challenges posed by the gigapixel resolution of WSIs and the limitations of existing multiple instance learning (MIL) methods.
  • The introduction of MambaMIL+ is significant as it aims to improve the accuracy and reliability of WSI analysis, which is crucial for diagnostic processes in pathology. By overcoming the constraints of previous models, it could lead to better clinical outcomes and more efficient workflows.
  • This development reflects a broader trend in computational pathology towards improving model interpretability and reliability, as seen in various studies exploring different frameworks and techniques. The integration of advanced methodologies, such as generative models and attention mechanisms, highlights the ongoing efforts to enhance diagnostic precision and address the complexities of high-resolution medical imaging.
— via World Pulse Now AI Editorial System

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